Rizzuto G. B Cell Responses to the Placenta and Fetus. Annu Rev Pathol. 2025 Jan;20(1):33-58. doi: 10.1146/annurev-pathmechdis-111523-023459. Epub 2025 Jan 2. Review. PubMed PMID: 39264989.

Liu YL, Praiss AM, Chiang S, Devereaux K, Huang J, Rizzuto G, Al-Rawi D, Weigelt B, Jewell E, Abu-Rustum NR, Aghajanian C. Gestational trophoblastic neoplasm: Patient outcomes and clinical pearls from a multidisciplinary referral center. Gynecol Oncol. 2025 Jan;192:171-177. doi: 10.1016/j.ygyno.2024.12.009. Epub 2024 Dec 13. PubMed PMID: 39674133; PubMed Central PMCID: PMC11761376.

Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik CR, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. Validation of a murine proteome-wide phage display library for identification of autoantibody specificities. JCI Insight. 2023 Dec 8;8(23). doi: 10.1172/jci.insight.174976. PubMed PMID: 37934865; PubMed Central PMCID: PMC10795829.

Haber LA, Dhaliwal G, Lo L, Rizzuto G. Evaluating a low anion gap: A practical approach. Cleve Clin J Med. 2023 Oct 2;90(10):619-623. doi: 10.3949/ccjm.90a.23035. Review. PubMed PMID: 37783490.

Greenbaum S, Averbukh I, Soon E, Rizzuto G, Baranski A, Greenwald NF, Kagel A, Bosse M, Jaswa EG, Khair Z, Kwok S, Warshawsky S, Piyadasa H, Goldston M, Spence A, Miller G, Schwartz M, Graf W, Van Valen D, Winn VD, Hollmann T, Keren L, van de Rijn M, Angelo M. A spatially resolved timeline of the human maternal-fetal interface. Nature. 2023 Jul;619(7970):595-605. doi: 10.1038/s41586-023-06298-9. Epub 2023 Jul 19. PubMed PMID: 37468587; PubMed Central PMCID: PMC10356615.

Glasner A, Rose SA, Sharma R, Gudjonson H, Chu T, Green JA, Rampersaud S, Valdez IK, Andretta ES, Dhillon BS, Schizas M, Dikiy S, Mendoza A, Hu W, Wang ZM, Chaudhary O, Xu T, Mazutis L, Rizzuto G, Quintanal-Villalonga A, Manoj P, de Stanchina E, Rudin CM, Pe'er D, Rudensky AY. Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies. Nat Immunol. 2023 Jun;24(6):1020-1035. doi: 10.1038/s41590-023-01504-2. Epub 2023 May 1. PubMed PMID: 37127830; PubMed Central PMCID: PMC10232368.

Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nat Immunol. 2023 Apr;24(4):676-689. doi: 10.1038/s41590-023-01444-x. Epub 2023 Mar 13. PubMed PMID: 36914891; PubMed Central PMCID: PMC10063449.

Hirschhorn D, Budhu S, Kraehenbuehl L, Gigoux M, Schröder D, Chow A, Ricca JM, Gasmi B, De Henau O, Mangarin LMB, Li Y, Hamadene L, Flamar AL, Choi H, Cortez CA, Liu C, Holland A, Schad S, Schulze I, Betof Warner A, Hollmann TJ, Arora A, Panageas KS, Rizzuto GA, Duhen R, Weinberg AD, Spencer CN, Ng D, He XY, Albrengues J, Redmond D, Egeblad M, Wolchok JD, Merghoub T. T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants. Cell. 2023 Mar 30;186(7):1432-1447.e17. doi: 10.1016/j.cell.2023.03.007. PubMed PMID: 37001503; PubMed Central PMCID: PMC10994488.

Rizzuto G, Erlebacher A. Trophoblast antigens, fetal blood cell antigens, and the paradox of fetomaternal tolerance. J Exp Med. 2022 May 2;219(5). doi: 10.1084/jem.20211515. Epub 2022 Apr 13. PubMed PMID: 35416936; PubMed Central PMCID: PMC9011327.

Rizzuto G, Brooks JF, Tuomivaara ST, McIntyre TI, Ma S, Rideaux D, Zikherman J, Fisher SJ, Erlebacher A. Establishment of fetomaternal tolerance through glycan-mediated B cell suppression. Nature. 2022 Mar;603(7901):497-502. doi: 10.1038/s41586-022-04471-0. Epub 2022 Mar 2. PubMed PMID: 35236989; PubMed Central PMCID: PMC9592526.

Hirschhorn D, Betof Warner A, Maniyar R, Chow A, Mangarin LM, Cohen AD, Hamadene L, Rizzuto GA, Budhu S, Suek N, Liu C, Houghton AN, Merghoub T, Wolchok JD. Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness. JCI Insight. 2021 Oct 22;6(20). doi: 10.1172/jci.insight.151035. PubMed PMID: 34676831; PubMed Central PMCID: PMC8564916.

Castel P, Dharmaiah S, Sale MJ, Messing S, Rizzuto G, Cuevas-Navarro A, Cheng A, Trnka MJ, Urisman A, Esposito D, Simanshu DK, McCormick F. RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33). doi: 10.1073/pnas.2103261118. PubMed PMID: 34380736; PubMed Central PMCID: PMC8379911.

Wang M, Ballah D, Wade A, Taylor AG, Rizzuto G, Li B, Lucero J, Chen LM, Kohi MP. Uterine Artery Embolization following Cesarean Delivery but prior to Hysterectomy in the Management of Patients with Invasive Placenta. J Vasc Interv Radiol. 2019 May;30(5):687-691. doi: 10.1016/j.jvir.2018.12.007. Epub 2019 Mar 25. PubMed PMID: 30922797; PubMed Central PMCID: PMC10468213.

Ategeka J, Wasswa R, Olwoch P, Kakuru A, Natureeba P, Muehlenbachs A, Kamya MR, Dorsey G, Rizzuto G. The prevalence of histologic acute chorioamnionitis among HIV infected pregnant women in Uganda and its association with adverse birth outcomes. PLoS One. 2019;14(4):e0215058. doi: 10.1371/journal.pone.0215058. eCollection 2019. PubMed PMID: 30973949; PubMed Central PMCID: PMC6459589.

Faralla C, Bastounis EE, Ortega FE, Light SH, Rizzuto G, Gao L, Marciano DK, Nocadello S, Anderson WF, Robbins JR, Theriot JA, Bakardjiev AI. Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing. PLoS Pathog. 2018 May;14(5):e1007094. doi: 10.1371/journal.ppat.1007094. eCollection 2018 May. PubMed PMID: 29847585; PubMed Central PMCID: PMC6044554.

Nancy P, Siewiera J, Rizzuto G, Tagliani E, Osokine I, Manandhar P, Dolgalev I, Clementi C, Tsirigos A, Erlebacher A. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. J Clin Invest. 2018 Jan 2;128(1):233-247. doi: 10.1172/JCI95937. Epub 2017 Nov 27. PubMed PMID: 29202469; PubMed Central PMCID: PMC5749543.

Kapisi J, Kakuru A, Jagannathan P, Muhindo MK, Natureeba P, Awori P, Nakalembe M, Ssekitoleko R, Olwoch P, Ategeka J, Nayebare P, Clark TD, Rizzuto G, Muehlenbachs A, Havlir DV, Kamya MR, Dorsey G, Gaw SL. Relationships between infection with Plasmodium falciparum during pregnancy, measures of placental malaria, and adverse birth outcomes. Malar J. 2017 Oct 5;16(1):400. doi: 10.1186/s12936-017-2040-4. PubMed PMID: 28982374; PubMed Central PMCID: PMC5629777.

Rizzuto G, Tagliani E, Manandhar P, Erlebacher A, Bakardjiev AI. Limited Colonization Undermined by Inadequate Early Immune Responses Defines the Dynamics of Decidual Listeriosis. Infect Immun. 2017 Aug;85(8). doi: 10.1128/IAI.00153-17. Print 2017 Aug. PubMed PMID: 28507070; PubMed Central PMCID: PMC5520438.

Natureeba P, Kakuru A, Muhindo M, Ochieng T, Ategeka J, Koss CA, Plenty A, Charlebois ED, Clark TD, Nzarubara B, Nakalembe M, Cohan D, Rizzuto G, Muehlenbachs A, Ruel T, Jagannathan P, Havlir DV, Kamya MR, Dorsey G. Intermittent Preventive Treatment With Dihydroartemisinin-Piperaquine for the Prevention of Malaria Among HIV-Infected Pregnant Women. J Infect Dis. 2017 Jul 1;216(1):29-35. doi: 10.1093/infdis/jix110. PubMed PMID: 28329368; PubMed Central PMCID: PMC5853208.

Faralla C, Rizzuto GA*, Lowe DE, Kim B, Cooke C, Shiow LR, Bakardjiev AI. InlP, a New Virulence Factor with Strong Placental Tropism. Infect Immun. 2016 Dec;84(12):3584-3596. doi: 10.1128/IAI.00625-16. Print 2016 Dec. PubMed PMID: 27736782; PubMed Central PMCID: PMC5116735.

Rizzuto GA, Kapidzic M, Gormley M, Bakardjiev AI. Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface. J Vis Exp. 2016 Jul 21;(113). doi: 10.3791/54237. PubMed PMID: 27500727; NIHMSID:NIHMS878647.

Kakuru A, Jagannathan P, Muhindo MK, Natureeba P, Awori P, Nakalembe M, Opira B, Olwoch P, Ategeka J, Nayebare P, Clark TD, Feeney ME, Charlebois ED, Rizzuto G, Muehlenbachs A, Havlir DV, Kamya MR, Dorsey G. Dihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy. N Engl J Med. 2016 Mar 10;374(10):928-39. doi: 10.1056/NEJMoa1509150. PubMed PMID: 26962728; PubMed Central PMCID: PMC4847718.

Malandro N, Budhu S, Kuhn NF, Liu C, Murphy JT, Cortez C, Zhong H, Yang X, Rizzuto G, Altan-Bonnet G, Merghoub T, Wolchok JD. Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion. Immunity. 2016 Jan 19;44(1):179-193. doi: 10.1016/j.immuni.2015.12.018. PubMed PMID: 26789923; PubMed Central PMCID: PMC4996670.

Kohi MP, Rizzuto GA, Fidelman N, Lucero J, Thiet MP. Retained Placenta Accreta Mimicking Choriocarcinoma. Case Rep Pathol. 2015;2015:167986. doi: 10.1155/2015/167986. Epub 2015 Oct 1. PubMed PMID: 26495146; PubMed Central PMCID: PMC4606209.

Diab A, Jenq RR, Rizzuto GA, Cohen AD, Huggins DW, Merghoub T, Engelhorn ME, Guevara-Patiño JA, Suh D, Hubbard-Lucey VM, Kochman AA, Chen S, Zhong H, Wolchok JD, van den Brink MR, Houghton AN, Perales MA. Enhanced responses to tumor immunization following total body irradiation are time-dependent. PLoS One. 2013;8(12):e82496. doi: 10.1371/journal.pone.0082496. eCollection 2013. PubMed PMID: 24349298; PubMed Central PMCID: PMC3861406.

Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD. Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment. Cancer Res. 2012 Feb 15;72(4):876-86. doi: 10.1158/0008-5472.CAN-11-1792. Epub 2011 Dec 15. PubMed PMID: 22174368; PubMed Central PMCID: PMC3288305.

Schaer DA, Li Y, Merghoub T, Rizzuto GA, Shemesh A, Cohen AD, Li Y, Avogadri F, Toledo-Crow R, Houghton AN, Wolchok JD. Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope. PLoS One. 2011;6(6):e21214. doi: 10.1371/journal.pone.0021214. Epub 2011 Jun 22. PubMed PMID: 21731676; PubMed Central PMCID: PMC3120835.

Nakahara T, Uchi H, Lesokhin AM, Avogadri F, Rizzuto GA, Hirschhorn-Cymerman D, Panageas KS, Merghoub T, Wolchok JD, Houghton AN. Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs. Blood. 2010 Jun 3;115(22):4384-92. doi: 10.1182/blood-2009-11-251231. Epub 2010 Feb 12. PubMed PMID: 20154220; PubMed Central PMCID: PMC2881499.

Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, Diab A, Rizzuto G, Duan F, Perales MA, Merghoub T, Houghton AN, Wolchok JD. Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. PLoS One. 2010 May 3;5(5):e10436. doi: 10.1371/journal.pone.0010436. PubMed PMID: 20454651; PubMed Central PMCID: PMC2862699.

Hirschhorn-Cymerman D, Rizzuto GA, Merghoub T, Cohen AD, Avogadri F, Lesokhin AM, Weinberg AD, Wolchok JD, Houghton AN. OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis. J Exp Med. 2009 May 11;206(5):1103-16. doi: 10.1084/jem.20082205. Epub 2009 May 4. PubMed PMID: 19414558; PubMed Central PMCID: PMC2715041.

Rizzuto GA, Merghoub T, Hirschhorn-Cymerman D, Liu C, Lesokhin AM, Sahawneh D, Zhong H, Panageas KS, Perales MA, Altan-Bonnet G, Wolchok JD, Houghton AN. Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response. J Exp Med. 2009 Apr 13;206(4):849-66. doi: 10.1084/jem.20081382. Epub 2009 Mar 30. PubMed PMID: 19332877; PubMed Central PMCID: PMC2715122.

Saenger YM, Li Y, Chiou KC, Chan B, Rizzuto G, Terzulli SL, Merghoub T, Houghton AN, Wolchok JD. Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma. Cancer Res. 2008 Dec 1;68(23):9884-91. doi: 10.1158/0008-5472.CAN-08-2233. PubMed PMID: 19047169; PubMed Central PMCID: PMC2742375.

Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, Sadelain M, Heller G, Zúñiga-Pflücker JC, Lu C, van den Brink MR. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nat Biotechnol. 2008 Apr;26(4):453-61. doi: 10.1038/nbt1395. Epub 2008 Mar 30. PubMed PMID: 18376399; PubMed Central PMCID: PMC2731996.

Engelhorn ME, Guevara-Patiño JA, Merghoub T, Liu C, Ferrone CR, Rizzuto GA, Cymerman DH, Posnett DN, Houghton AN, Wolchok JD. Mechanisms of immunization against cancer using chimeric antigens. Mol Ther. 2008 Apr;16(4):773-81. doi: 10.1038/mt.2008.8. Epub 2008 Feb 26. PubMed PMID: 18301399; PubMed Central PMCID: PMC4399381.

Zakrzewski JL, Kochman AA, Lu SX, Terwey TH, Kim TD, Hubbard VM, Muriglan SJ, Suh D, Smith OM, Grubin J, Patel N, Chow A, Cabrera-Perez J, Radhakrishnan R, Diab A, Perales MA, Rizzuto G, Menet E, Pamer EG, Heller G, Zúñiga-Pflücker JC, Alpdogan O, van den Brink MR. Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nat Med. 2006 Sep;12(9):1039-47. doi: 10.1038/nm1463. Epub 2006 Aug 27. PubMed PMID: 16936725.

Cohen AD, Diab A, Perales MA, Wolchok JD, Rizzuto G, Merghoub T, Huggins D, Liu C, Turk MJ, Restifo NP, Sakaguchi S, Houghton AN. Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity. Cancer Res. 2006 May 1;66(9):4904-12. doi: 10.1158/0008-5472.CAN-05-2813. PubMed PMID: 16651447; PubMed Central PMCID: PMC2242844.

Guevara-Patiño JA, Engelhorn ME, Turk MJ, Liu C, Duan F, Rizzuto G, Cohen AD, Merghoub T, Wolchok JD, Houghton AN. Optimization of a self antigen for presentation of multiple epitopes in cancer immunity. J Clin Invest. 2006 May;116(5):1382-90. doi: 10.1172/JCI25591. Epub 2006 Apr 13. PubMed PMID: 16614758; PubMed Central PMCID: PMC1435720.

Uchi H, Stan R, Turk MJ, Engelhorn ME, Rizzuto GA, Goldberg SM, Wolchok JD, Houghton AN. Unraveling the complex relationship between cancer immunity and autoimmunity: lessons from melanoma and vitiligo. Adv Immunol. 2006;90:215-41. doi: 10.1016/S0065-2776(06)90006-6. Review. PubMed PMID: 16730265.

Rivera A, Van Epps HL, Hohl TM, Rizzuto G, Pamer EG. Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia. Infect Immun. 2005 Nov;73(11):7170-9. doi: 10.1128/IAI.73.11.7170-7179.2005. PubMed PMID: 16239511; PubMed Central PMCID: PMC1273880.

Turk MJ, Guevara-Patiño JA, Rizzuto GA, Engelhorn ME, Sakaguchi S, Houghton AN. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med. 2004 Sep 20;200(6):771-82. doi: 10.1084/jem.20041130. PubMed PMID: 15381730; PubMed Central PMCID: PMC2211964.

Rizzuto G, Li L, Steiner N, Slack R, Tang T, Heine U, Lin YS, Ng J, Hartzman R, Hurley CK. Diversity within the DRB1*08 allele family in four populations from a United States hematopoietic stem cell donor database and characterization of five novel DRB1*08 alleles. Hum Immunol. 2003 Jun;64(6):607-13. doi: 10.1016/s0198-8859(03)00069-7. PubMed PMID: 12770791.

Bradshaw D, Gans CP, Jones P, Rizzuto G, Steiner N, Mitton W, Ng J, Koester R, Hartzman RJ, Hurley CK. Novel HLA-A locus alleles including A*01012, A*0306, A*0308, A*2616, A*2617, A*3009, A*3206, A*3403, A*3602 and A*6604. Tissue Antigens. 2002 Apr;59(4):325-7. doi: 10.1034/j.1399-0039.2002.590413.x. PubMed PMID: 12135434.

Steiner NK, Jones P, Kosman C, Edson S, Rizzuto G, Gans CP, Mitton W, Koester R, Rodriguez-Marino SG, Ng J, Hartzman RJ, Hurley CK. Novel HLA-B alleles associated with antigens in the 7C CREG. Tissue Antigens. 2001 May;57(5):486-8. doi: 10.1034/j.1399-0039.2001.057005486.x. PubMed PMID: 11556977.

Steiner NK, Kosman C, Jones PF, Gans CP, Rodriguez-Marino SG, Rizzuto G, Baldassarre LA, Edson S, Koester R, Sese D, Mitton W, Ng J, Hartzman RJ, Hurley CK. Twenty-nine new HLA-B alleles associated with antigens in the 5C CREG. Tissue Antigens. 2001 May;57(5):481-5. doi: 10.1034/j.1399-0039.2001.057005481.x. PubMed PMID: 11556976.

Hurley CK, Steiner N, Gans CP, Kosman C, Mitton W, Koester R, Jones P, Edson S, Rizzuto G, Hartzman RJ, Ng J, Rodriguez-Marino SG. Twelve novel HLA-B*15 alleles carrying previously observed sequence motifs are placed into B*15 subgroups. Tissue Antigens. 2001 May;57(5):474-7. doi: 10.1034/j.1399-0039.2001.057005474.x. PubMed PMID: 11556974.

Steiner NK, Gans CP, Kosman C, Baldassarre LA, Edson S, Jones PF, Rizzuto G, Pimtanothai N, Koester R, Mitton W, Ng J, Hartzman RJ, Hurley CK. Novel HLA-B alleles associated with antigens in the 8C CREG. Tissue Antigens. 2001 Apr;57(4):373-5. doi: 10.1034/j.1399-0039.2001.057004373.x. PubMed PMID: 11380951.

Pimtanothai N, Rizzuto GA, Slack R, Steiner NK, Kosman CA, Jones PF, Koester R, Ng J, Hartzman RJ, Katovich Hurley C. Diversity of alleles encoding HLA-B40: relative frequencies in united states populations and description of five novel alleles. Hum Immunol. 2000 Aug;61(8):808-15. doi: 10.1016/s0198-8859(00)00149-x. PubMed PMID: 10980391.